Top Billed Cast

1. 

   Drew Barrymore

   Chloe (voice)

2. 

   Piper Perabo

   Rachel Ashe Lynn

3. 

   Andy García

   Delgado (voice)

4. 

   George Lopez

   Papi (voice)

5. 

   Paul Rodríguez

   Chico (voice)

6. 

   Plácido Domingo

   Monte (voice)

7. 

   Edward James Olmos

   Diablo (voice)

8. 

   Loretta Devine

   Delta (voice)

9. 

   Jamie Lee Curtis

   Aunt Viv

10. 

    Luis Guzmán

    Chucho (voice)

11. 

    Eddie 'Piolin' Sotelo

    Rafa (voice)

12. 

    Carlos Juvera

    Tomás (voice)

13. 

    Grey DeLisle

    Mother Dog (voice)

14. 

    Manolo Cardona

    Sam Cortez

15. 

    Leslie Mann

    Bimini (uncredited)

16. 

    Cheech Marin

    Manuel (voice)

17. 

    Michael Urie

    Sebastian (voice)

18. 

    José María Yázpik

    Vasquez

19. 

    Maury Sterling

    Rafferty

20. 

    Jesús Ochoa

    Officer Ramirez

21. 

    Eugenio Derbez

    Store Owner

22. 

    Omar Leyva

    Ranger

23. 

    Naomy Romo

    Ranger

24. 

    Ali Hillis

    Angela

25. 

    Marguerite Moreau

    Blair

26. 

    Nick Zano

    Bryan

27. 

    Gina Gallego

    Shelter Director

28. 

    Alberto Reyes

    Bellman

29. 

    Brandon Keener

    Waiter

30. 

    Sal Lopez

    Ring Announcer

31. 

    Giovanna Acha Aleman

    Museum Guide

32. 

    Jack Plotnick

    Dog Nanny

33. 

    Randall England

    Butler

34. 

    James P. Bennett

    Bull Fighter (uncredited)

35. 

    Mary Paz Mata

    Shaman Lady

36. 

    Tomihuatzi Xelhuantzi

    Museum Security Guard

37. 

    Mayra Sérbulo

    Poor Woman

38. 

    Fernando Manzano

    Desk Sergeant