Top Billed Cast

1. 

   Kyrie Irving

   Uncle Drew

2. 

   Lil Rel Howery

   Dax Winslow

3. 

   Shaquille O'Neal

   Big Fella

4. 

   Chris Webber

   Preacher

5. 

   Reggie Miller

   Lights

6. 

   Nate Robinson

   Boots

7. 

   Lisa Leslie

   Betty Lou

8. 

   Erica Ash

   Maya

9. 

   Tiffany Haddish

   Jess

10. 

    Nick Kroll

    Mookie Bass

11. 

    Aaron Gordon

    Casper Jones

12. 

    Mike Epps

    Louis

13. 

    JB Smoove

    Angelo

14. 

    Wesley Witherspoon

    Mario

15. 

    Thomas Mills

    Duke Tango

16. 

    Selema Masekela

    Sal Masekela

17. 

    Adam Lazarre-White

    Frankie the Tournament Director / Narrator

18. 

    Lavar Walker

    Marty the Manager

19. 

    John Calipari

    John Calipari

20. 

    Joe Hammond

    Joe Hammond

21. 

    Scoop Jackson

    Scoop Jackson

22. 

    Pee Wee Kirkland

    Pee Wee Kirkland

23. 

    Earl Monroe

    Earl Monroe

24. 

    Chris Mullin

    Chris Mullin

25. 

    Maurice G. Smith

    Dominic 'The Glove' Willis

26. 

    Kevin Benton

    Zeke 'The Mouth' Murray

27. 

    Bill Walton

    Bill Walton

28. 

    George Gervin

    George Gervin

29. 

    Steve Nash

    Steve Nash

30. 

    David Robinson

    David Robinson

31. 

    Jerry West

    Jerry West

32. 

    Rick Barry

    Rick Barry

33. 

    Dikembe Mutombo

    Dikembe Mutombo

34. 

    NeNe Leakes

    Nene Leakes

35. 

    Aiden Williams

    Adopted Kid

36. 

    Tinuke Adetunji

    Angelo's Girl

37. 

    Deadra Moore

    Desk Nurse

38. 

    Enoch King

    Baby's Dad

39. 

    Crystal Lee Brown

    Mom

40. 

    Kenneth Crudup

    Baller

41. 

    Mark Robert Ellis

    Basketball Coach (as Mark Ellis)

42. 

    Terence Rosemore

    Customer #1

43. 

    Terrence 'T.C.' Carson

    Customer #2

44. 

    Rick Ross

    Customer #3

45. 

    Trey Griffith

    Dax - 4 Years Old

46. 

    Judah Howery

    Dax - 10 Years Old

47. 

    Ashton Tyler

    Young Dax

48. 

    Carrie Walrond Hood

    Foot Locker Mother

49. 

    Lorenzo Davis

    Opponent

50. 

    Brian Kortovich

    Opponent

51. 

    Keith Jamal Evans

    Other Kid (as Keith Evans)

52. 

    Josh Henry

    Paramedic

53. 

    Phil Ductan

    Player

54. 

    Elijah Everett

    Player

55. 

    Rocco Poveromo

    Referee

56. 

    Barry Rohrssen

    Referee

57. 

    Scott Van Pelt

    Scott Van Pelt - ESPN Host (uncredited)

58. 

    Jamel Chambers

    Angry Fan

59. 

    Alannah Wilhite

    Girl in club

60. 

    Matt McHugh

    Security Guard

61. 

    Dario A. Lee

    The Destroyer (uncredited)